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. 2020 Sep 15;46(5):1633–1643. doi: 10.3892/ijmm.2020.4726

Figure 1.

Figure 1

(A) Domain structures of MMLV RT and AMV RT. (B) A sequence alignment of MMLV RT and AMV RT. A homology search was performed using the search program DNA Data Bank of Japan (DDBJ) CLUSTALW and was revised based on the data of X-ray crystallographic analysis of MMLV RT. Asterisks show homologous amino acid residues. The amino acid residues to be mutated for thermostabilization are marked in bold and are underlined. Leu603 and Glu607 in ref. 26 correspond to Leu593 and Glu597, respectively.