TABLE 1.
Patient demographics
| EC-AIA n (%) | Control n (%) | P value | |
|---|---|---|---|
| Number | 46 | 1294 | |
| Mean age (years) | 58.9 ± 9.9 | 55.3 ± 11.4 | 0.032 |
| <50 | 7 (15.6) | 384 (29.7) | |
| 50–59 | 16 (35.5) | 466 (36.0) | |
| ≥60 | 22 (48.9) | 444 (34.3) | |
| Missing | 1 | 0 | |
| Ethnicity | <0.001 | ||
| Caucasian | 14 (31.8) | 176 (13.6) | |
| African American | 3 (6.8) | 38 (2.9) | |
| Hispanic | 2 (4.6) | 566 (43.8) | |
| Asian | 25 (56.8) | 514 (39.7) | |
| Missing | 2 | 0 | |
| Histology | 0.002 | ||
| Endometrioid | 35 (77.8) | 1063 (82.1) | |
| Serous | 7 (15.5) | 77 (6.0) | |
| Clear cell | 3 (6.7) | 28 (2.2) | |
| Other | 0 | 126 (9.7) | |
| Missing | 1 | 0 | |
| Grade | 0.16 | ||
| Low grade | 28 (68.3) | 1005 (77.7) | |
| High grade | 13 (31.7) | 289 (22.3) | |
| Missing | 5 | 0 | |
| Deep myometrial invasion | 0.002 | ||
| No | 15 (48.4) | 923 (73.4) | |
| Yes | 16 (51.6) | 335 (26.6) | |
| Missing | 15 | 36 | |
| Stage | 0.63 | ||
| I | 30 (73.2) | 921 (71.2) | |
| II | 1 (2.4) | 100 (7.8) | |
| III | 6 (14.6) | 185 (14.3) | |
| IV | 4 (9.8) | 87 (6.7) | |
| Missing | 5 | 1 | |
| Nodal metastasisa | 0.075 | ||
| Negative | 24 (72.7) | 701 (84.4) | |
| Positive | 9 (27.3) | 130 (15.6) | |
| Not performed | 13 | 463 | |
| ER expression | <0.001 | ||
| Negative | 12 (85.7) | 57 (15.4) | |
| Positive | 2 (14.3) | 313 (84.6) | |
| Not evaluated | 32 | 924 |
Student t test or Chi square was performed for P values
EC-AIA Endometrial cancer arising in adenomyosis, ER estrogen receptor
a
Nodal metastasis for pelvic and/or paraaortic lymph nodes