Fig 3. Percentage of low-covered bases per gene for each method.

The genes were ordered by the percentage of low-covered bases. The red dots represent whole genome sequencing (WGS), the green triangles represent whole exome sequencing (WES), and the blue squares represent HaloPlex target enrichment sequencing (HES). Gene names in both bold and italic are found in the ACMG SF v.2.0 list of genes published by the American College of Medical Genetics and Genomics (ACMG).