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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Chem Soc Rev. 2020 Sep 1;49(17):6402–6442. doi: 10.1039/d0cs00705f

Figure 1.

Figure 1.

Overview of microfluidic device designs to mimic lumen-structured organs. Two-dimensional (2D) organ geometries include cells cultured on microchannel surfaces, porous membranes, and gel interfaces. Three-dimensional (3D) organ geometries include cell-lined channels, cell-filled channels, and lumens with square and circular cross-sections.