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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: Chem Soc Rev. 2020 Sep 1;49(17):6402–6442. doi: 10.1039/d0cs00705f

Figure 9.

Figure 9.

Organotypic bronchiole model to study multi-kingdom interactions in the human lung. (a) Schematic of organotypic bronchiole model. A central bronchiole epithelial lumen filled with air is flanked by two endothelial vessels. (b) Representative image of organotypic bronchiole model device with air in the epithelial lumen and media in the endothelial lumens. Staining of nuclei (Hoechst, blue), CD31 (green), and EpCAM (red). Scale bars are 500 μm. (c) Zoomed image of epithelium in the center lumen (left) and endothelium in the side lumens (right). Scale bars are 200 μm. Adapted with permission from Barkal, 201792.