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. Author manuscript; available in PMC: 2020 Sep 28.
Published in final edited form as: Nat Rev Chem. 2019 May 7;3(6):347–360. doi: 10.1038/s41570-019-0099-x

Figure 3. Overview of intramolecular C–H insertion reactions.

Figure 3.

a: Early example using an achiral catalyst. b: Enantioselective C–H functionalization examples using chiral dirhodium catalysts. c: Example of a key carbene C–H functionalization step in the total synthesis of (+)-isolauricerisinol.