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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: Environ Int. 2020 Feb 18;137:105531. doi: 10.1016/j.envint.2020.105531

Table 3:

Odds ratios (95% CI) of incident diabetes or diabetes + IFG at visit 5 by urinary ΣAs at baseline

Diabetes (79/387) Diabetes and IFG (182/284)
(n = 466) Maternal ΣAs Offspring ΣAs Maternal ΣAs Offspring ΣAs
Model 1 1.43 (1.16, 1.78) 1.27 (1.03, 1.58) 1.45 (1.15, 1.83) 1.18 (0.99, 1.40)
Model 2 1.43 (1.15, 1.78) 1.26 (1.01, 1.56) 1.42 (1.18 1.71) 1.15 (0.96, 1.38)
Model 3 1.35 (1.07, 1.69) 1.15 (0.92, 1.43) 1.42 (1.18 1.72) 1.03 (0.85, 1.24)
Model 4 1.20 (0.95, 1.53) 1.26 (1.00, 1.58) 1.32 (1.09 1.59) 1.12 (0.91, 1.37)
Model 5 1.18 (0.94, 1.49) 1.23 (0.98, 1.54) 1.30 (1.08 1.56) 1.09 (0.88, 1.35)

Model 1 is adjusted for offspring sex and age at baseline visit, and maternal eGFR at baseline for maternal models or offspring eGFR for offspring models

Model 2 = Model 1 + maternal BMI (kg/m2) and maternal fasting glucose (mg/dL) at baseline

Model 3 = Model 2 + offspring ΣAs in maternal models or maternal ΣAs in offspring models (fully adjusted model)

Model 4 = Model 3 + offspring BMI at baseline

Model 5 = Model 3 + offspring waist circumference at baseline

Odds ratios (95% CI) are reported per an increase equal to the IQR in ΣAs distribution.

Numbers in brackets are cases and non-cases

GEE used to account for family clustering.