Table 3:
Diabetes (79/387) | Diabetes and IFG (182/284) | |||
---|---|---|---|---|
(n = 466) | Maternal ΣAs | Offspring ΣAs | Maternal ΣAs | Offspring ΣAs |
Model 1 | 1.43 (1.16, 1.78) | 1.27 (1.03, 1.58) | 1.45 (1.15, 1.83) | 1.18 (0.99, 1.40) |
Model 2 | 1.43 (1.15, 1.78) | 1.26 (1.01, 1.56) | 1.42 (1.18 1.71) | 1.15 (0.96, 1.38) |
Model 3 | 1.35 (1.07, 1.69) | 1.15 (0.92, 1.43) | 1.42 (1.18 1.72) | 1.03 (0.85, 1.24) |
Model 4 | 1.20 (0.95, 1.53) | 1.26 (1.00, 1.58) | 1.32 (1.09 1.59) | 1.12 (0.91, 1.37) |
Model 5 | 1.18 (0.94, 1.49) | 1.23 (0.98, 1.54) | 1.30 (1.08 1.56) | 1.09 (0.88, 1.35) |
Model 1 is adjusted for offspring sex and age at baseline visit, and maternal eGFR at baseline for maternal models or offspring eGFR for offspring models
Model 2 = Model 1 + maternal BMI (kg/m2) and maternal fasting glucose (mg/dL) at baseline
Model 3 = Model 2 + offspring ΣAs in maternal models or maternal ΣAs in offspring models (fully adjusted model)
Model 4 = Model 3 + offspring BMI at baseline
Model 5 = Model 3 + offspring waist circumference at baseline
Odds ratios (95% CI) are reported per an increase equal to the IQR in ΣAs distribution.
Numbers in brackets are cases and non-cases
GEE used to account for family clustering.