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. 2020 Sep 14;35(38):e343. doi: 10.3346/jkms.2020.35.e343

Table 1. Characteristics and laboratory findings of patients with COVID-19.

Characteristics Mild/moderate cases (n = 20) Severe/critical cases (n = 8) P value
Characteristics
Age, yr 53.5 (21–97) 63.5 (36–78) 0.381
Male 10/20 (50) 4/8 (50) 1.000
Body mass index, kg/m2 23.3 (11.8–30.8) 22.8 (20.3–31.0) 0.359
Fever 2/20 (10) 7/8 (87.5) < 0.001
Days from symptom onset to sampling 5.5 (5–10) 7.0 (5–11) 0.371
Days from symptom onset to mechanical ventilator - 10 (8–12) -
Modified Early Warning Score 1 (1–2) 3 (2–3) < 0.001
National Early Warning Score 0 (0–2) 5 (1–8) < 0.001
Sequential Organ Failure Assessment score 0 (0–1) 2.5 (0–6) < 0.001
Underlying conditions
Cardiovascular diseasea 6/20 (30) 3/8 (37.5) 0.516
Cerebrovascular diseaseb 2/20 (10) 2/8 (25) 0.318
Diabetes mellitus 2/20 (10) 1/8 (12.5) 0.652
Chronic kidney disease 0/20 (0) 1/8 (12.5) 0.286
Charlson comorbidity index 1.0 (0–5) 2.5 (0–6) 0.136
Laboratory findings
White blood cell count, × 103/mm3 4.60 (3.0–8.66) 5.44 (2.8–11.76) 0.576
Neutrophil, × 103/mm3 2.97 (1.9–6.08) 3.82 (2.1–10.43) 0.242
Lymphocyte, × 103/mm3 1.30 (0.5–2.2) 1.03 (0.6–1.93) 0.186
Neutrophil-to-lymphocyte ratio 2.29 (1.05–6.0) 3.42 (2.2–10.98) 0.042
Monocyte, × 103/mm3 0.300 (0.1–0.92) 0.455 (0.1–0.94) 0.601
Monocyte, % 6.65 (0.3–19.8) 6.65 (3.1–14.3) 0.901
Platelet, × 103/mm3 180.0 (107–365) 170.5 (97–269) 0.387
Alanine aminotransferase, U/L 21 (13–50) 27 (19–110) 0.098
Aspartate aminotransferase, U/L 19 (12–121) 20.5 (8–53) 0.858
Albumin, g/dL 4.15 (3.1–4.6) 3.15 (2.3–4.1) 0.001
Total bilirubin, mg/dL 0.20 (0.1–1.23) 0.54 (0.1–2.27) 0.575
Lactate dehydrogenase, U/L 363.5 (280–554) 596.0 (340–1,461) 0.001
C-reactive protein, mg/dL 0.3 (0.3–1.7) 7.9 (2.3–12.4) < 0.001

Data are presented as medians (ranges) or numbers (%). For asymptomatic patients in the mild/moderate group, a time of diagnosis with COVID-19 was used as illness onset.

COVID-19 = coronavirus disease 2019.

a Including hypertension; bIncluding dementia and schizophrenia.

HHS Vulnerability Disclosure