Table 1. Characteristics and laboratory findings of patients with COVID-19.
Characteristics | Mild/moderate cases (n = 20) | Severe/critical cases (n = 8) | P value | ||
---|---|---|---|---|---|
Characteristics | |||||
Age, yr | 53.5 (21–97) | 63.5 (36–78) | 0.381 | ||
Male | 10/20 (50) | 4/8 (50) | 1.000 | ||
Body mass index, kg/m2 | 23.3 (11.8–30.8) | 22.8 (20.3–31.0) | 0.359 | ||
Fever | 2/20 (10) | 7/8 (87.5) | < 0.001 | ||
Days from symptom onset to sampling | 5.5 (5–10) | 7.0 (5–11) | 0.371 | ||
Days from symptom onset to mechanical ventilator | - | 10 (8–12) | - | ||
Modified Early Warning Score | 1 (1–2) | 3 (2–3) | < 0.001 | ||
National Early Warning Score | 0 (0–2) | 5 (1–8) | < 0.001 | ||
Sequential Organ Failure Assessment score | 0 (0–1) | 2.5 (0–6) | < 0.001 | ||
Underlying conditions | |||||
Cardiovascular diseasea | 6/20 (30) | 3/8 (37.5) | 0.516 | ||
Cerebrovascular diseaseb | 2/20 (10) | 2/8 (25) | 0.318 | ||
Diabetes mellitus | 2/20 (10) | 1/8 (12.5) | 0.652 | ||
Chronic kidney disease | 0/20 (0) | 1/8 (12.5) | 0.286 | ||
Charlson comorbidity index | 1.0 (0–5) | 2.5 (0–6) | 0.136 | ||
Laboratory findings | |||||
White blood cell count, × 103/mm3 | 4.60 (3.0–8.66) | 5.44 (2.8–11.76) | 0.576 | ||
Neutrophil, × 103/mm3 | 2.97 (1.9–6.08) | 3.82 (2.1–10.43) | 0.242 | ||
Lymphocyte, × 103/mm3 | 1.30 (0.5–2.2) | 1.03 (0.6–1.93) | 0.186 | ||
Neutrophil-to-lymphocyte ratio | 2.29 (1.05–6.0) | 3.42 (2.2–10.98) | 0.042 | ||
Monocyte, × 103/mm3 | 0.300 (0.1–0.92) | 0.455 (0.1–0.94) | 0.601 | ||
Monocyte, % | 6.65 (0.3–19.8) | 6.65 (3.1–14.3) | 0.901 | ||
Platelet, × 103/mm3 | 180.0 (107–365) | 170.5 (97–269) | 0.387 | ||
Alanine aminotransferase, U/L | 21 (13–50) | 27 (19–110) | 0.098 | ||
Aspartate aminotransferase, U/L | 19 (12–121) | 20.5 (8–53) | 0.858 | ||
Albumin, g/dL | 4.15 (3.1–4.6) | 3.15 (2.3–4.1) | 0.001 | ||
Total bilirubin, mg/dL | 0.20 (0.1–1.23) | 0.54 (0.1–2.27) | 0.575 | ||
Lactate dehydrogenase, U/L | 363.5 (280–554) | 596.0 (340–1,461) | 0.001 | ||
C-reactive protein, mg/dL | 0.3 (0.3–1.7) | 7.9 (2.3–12.4) | < 0.001 |
Data are presented as medians (ranges) or numbers (%). For asymptomatic patients in the mild/moderate group, a time of diagnosis with COVID-19 was used as illness onset.
COVID-19 = coronavirus disease 2019.
a Including hypertension; bIncluding dementia and schizophrenia.