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. 2020 Sep 16;23(10):101562. doi: 10.1016/j.isci.2020.101562

Figure 4.

Figure 4

Application of a Spatially Resolved 53-Genes Signature Discriminating DZ and LZ to 543 GC-Related DLBCL and DH Cases (GSE117556)

(A) Unsupervised clustering analysis of the 543 GC-DLBCL and DH cases based on the DZ/LZ signature identifies two distinct clusters (DZ-like and LZ-like).

(B and C) Bar plots showing the differential enrichment in molecular high-grade (MHG, B) and double-hit (DH, C) cases between the DZ-like and LZ-like clusters.

(D) Survival analysis showing significantly different overall survival in the LZ-like and DZ-like clusters.