Figure 4.

ST Analysis on Hippocampi Regions Reveals Differences among Stress Response Signaling Genes Globally and Regionally

(A) Heatmap of the spatially differentially expressed genes found in the hippocampi clustered by rows. Graphic colorized by normalized expression and separated by color-coded genotype and cluster region.

(B) Heatmap of log2-fold-change values of genes shown in (A) clustered by rows and columns.

(C) Graphic representation of normalized gene expression of selected genes overlaid onto brain sections. The genes represent the types of data seen. Shown are Gabra2, Pkm, Paip1, Glo1, Thy1, Wbp1, Sgk1, Bok, Jun, and Lpl. H&E-stained brain slices are shown on the right.

See also Figures S4 and S6–S9.