Figure 3.
PMv and Arc Transcriptional Changes during Pubertal Transition in Wild-Type Female Mice
(A) Venn diagram of differentially expressed genes (DEGs) in PMv and Arc between prepubertal (PP) and diestrous (Di) females.
(B) Amount and percentage of up- and downregulated DEGs.
(C) Hierarchical clustering of the top 500 expressed genes.
(D and E) DEGs between PP and Di mice expressed (D) only in the PMv or (E) only in the Arc. Blue lines: genes associated with both reproduction and development. Purple lines: genes associated with development.
(F) Heatmap showing relative gene expression of common DEGs in the PMv and Arc enriched in development and reproduction (GO 0032502 and 0000003, respectively).