Figure 1.

¹⁸F-FDG uptake in 7- and 12-month-old WT and 5XFAD mice. (A) 7-month-old 5XFAD mice showed a significantly lower SUVglc in the whole brain compared to age-matched WT mice. (B) 12-month-old 5XFAD mice showed a significantly lower SUVglc in the whole brain compared to age-matched WT mice. (C) 7-month-old 5XFAD mice showed a significantly lower SUVglc in all brain regions except for cortex and olfactory bulb compared to age-matched WT mice. (D) 12-month-old 5XFAD mice showed a significantly lower SUVglc in all brain regions compared to age-matched WT mice except for forebrain and olfactory bulb. Unpaired t-test; *p < 0.05; **p < 0.01; data presented as mean +/- SEM.