Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Sep 28;10:15919. doi: 10.1038/s41598-020-72792-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Bifidobacterium longum subsp. infantis metabolic pathway for utilization of 2′FL, 3FL, DFL and their constituent monosaccharides. FLs are internalized by ABC transporters and hydrolyzed intracellularly by a set of β-galactosidases and α-fucosidases of various substrate specificities (listed in Fig. 7). The resultant monosaccharides enter the Bifid shunt and fermentative pathways characteristic of this taxon. L-fucose catabolism in bifidobacteria has not yet been fully elucidated and is depicted as predicted in^19,23 with modifications. Known or predicted genes implicated in L-fucose catabolism are shown as Blon IDs. The central role of the pyruvate node for metabolism of small fucosylated HMOs is highlighted. Dissipation of the excess of L-fucose via yet unidentified efflux transporters for fucose and pyruvate is shown on the left. Enzymes are in gold, compounds in black, secreted fermentation end products are in green or red (for pyruvate). See Supplemental Table 2 for explanation of abbreviations.