Table 2.
AT classification.
| Total N | A−T− | A+T− | A+T+ | A−T+ | p | |
|---|---|---|---|---|---|---|
| The whole cohort (n [%]) | 412 (100) | 87 (21.1) | 109 (26.5) | 165 (40.0) | 51 (12.4) | |
| sTREM2 ng/ml (mean [SD]) | 8.1 (3.6) | 7.7 (3.6) | 10.7 (4.9) | 10.8 (4.1) | < 0.001a | |
| AD-MCI patients (n [%]) | 62 (100) | 12 (19.4) | 21 (33.9) | 25 (40.3) | 4 (6.5) | |
| sTREM2 ng/ml (mean [SD]) | 7.5 (3.6) | 8.7 (3.7) | 11.9 (4.9) | 10.5 (4.6) | 0.02a | |
| AD dementia patients (n [%]) | 237 (100) | 23 (9.7) | 72 (30.4) | 127 (53.6) | 15 (6.3) | |
| sTREM2 ng/ml (mean [SD]) | 8.6 (5.2) | 7.7 (3.7) | 10.5 (5.0) | 10.8 (3.9) | < 0.001a | |
| Cognitively unimpaired (n [%]) | 113 (100) | 52 (46.0) | 16(14.2) | 13 (11.5) | 32 (28.2) | |
| sTREM2 ng/ml (mean [SD]) | 7.9 (2.7) | 6.7 (2.4) | 10.3 (4.0) | 10.9 (4.2) | < 0.001a |
Bold values are statistically significant (p ≤ 0.05).
MCI mild cognitive impairment, AD Alzheimer's disease.
a = Kruskal–Wallis test, % = valid percent without missing.