Table 4.
Comparison of the clinical outcome for the patients with high P4 levels on the day of hCG injection (n = 149) between P4 ratio ≤1.62 and >1.62 groups.
| P4 ratio | ≤1.62 | >1.62 | P-value |
|---|---|---|---|
| N (patients, cycles) | 60 | 89 | – |
| Age (years) | 33.1 ± 3.6 | 33.1 ± 3.4 | 0.898 |
| P4 level I (ng/ml) | 1.82 ± 0.84 | 0.82 ± 0.43 | <0.001 |
| P4 level II (ng/ml, hCG day) | 2.02 ± 0.88 | 2.87 ± 1.34 | <0.001 |
| LH (mIU/ml, hCG day) | 2.3 ± 1.6 | 2.8 ± 2.1 | 0.165 |
| E2 (pg/ml, hCG day) | 2,441 ± 905 | 1,957 ± 1,017 | 0.004 |
| Total FSH dosage | 2,880 ± 565 | 2,804 ± 858 | 0.176 |
| Oocyte number | 11.0 ± 3.2 | 9.8 ± 3.6 | 0.051 |
| MII no. | 8.3 ± 3.2 | 7.7 ± 3.4 | 0.174 |
| Total embryo no. | 6.3 ± 2.8 | 6.0 ± 2.8 | 0.352 |
| Day 3 good embryo rate | 62.2 ± 25.0 | 65.3 ± 27.8 | 0.434 |
| ET no. | 3.1 ± 0.6 | 3.1 ± 0.7 | 0.645 |
| Implantation rate | 10.3 (19/184) | 29.2 (81/277) | <0.001 |
| Pregnancy rate | 20.0 (12/60) | 59.6 (53/89) | <0.001 |
| Abortion rate | 16.7 (2/12) | 26.4 (14/53) | 0.714 |
| Live birth rate | 15.0 (9/60) | 43.8 (39/89) | <0.001 |
| Gestational age (weeks) | 37.7 ± 1.5 | 36.7 ± 2.3 | 0.255 |
| Birth weight (g) | 2,821 ± 477 | 2,648 ± 687 | 0.452 |
Statistical methods: Mann-Whitney test, χ2 test and Fisher's exact test.
In the table, percentages are used to describe categorical data and mean ± SD used to describe a set of continuous data.
P4 level I, the progesterone levels on 2 days prior to hCG day; P4 level II, progesterone level on the day of hCG administration; FSH, follicle stimulating hormone; E2, estrogen; LH, luteinizing hormone; P4, progesterone; ET, embryo transfer; MII, oocyte with metaphase II.