Supplementary Fig. S3.

IL-1β and TNF-α promote proliferative dominance of mammary epithelial cells in a HER2-dependent manner. (A) HB2 and (B) MCF10A cell lines and their GFP-expressing (HER2+)GFP variants were mixed in a ratio of 1:1 and embedded in 3D matrigel. After 8 days of growth in the presence of IL-1β (10 ng/ml) or TNF-α (10 ng/ml) representative images were taken and colony size analysed using ImageJ software. Data are expressed as means ± SD (n = 3), ***p < 0.001.