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. 2020 Sep 24;13:9455–9463. doi: 10.2147/OTT.S259853

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© 2020 Yan et al.

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CM from exendin-4-treated PSCs inhibits pancreatic cancer cell proliferation, migration, and invasion. PANC-1 and SW1990 cells were incubated with CM from PSCs or exendin-4-treated PSCs, or AMD3100-treated cells were incubated with CM from PSCs. (A) Cell proliferation determined by CCK-8 assay (*P<0.05, by Student’s t-test vs control; ^&P<0.05, by Student’s t-test vs CM_PSC). (B) Cell migration determined by Transwell migration assay (**P<0.01, by Student’s t-test vs control; ^&&P<0.01, by Student’s t-test vs CM_PSC). (C) Cell invasion determined by Transwell invasion assay (**P<0.01, by Student’s t-test vs control; ^&&P<0.01, by Student’s t-test vs CM_PSC). Data represent mean ± SD from three independent experiments.