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. 2020 Sep 15;7:546. doi: 10.3389/fmed.2020.00546

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Copyright © 2020 Fernandes, Vale, Guzen, Pinheiro, Cobucci and de Azevedo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Azithromycin activity in maintaining the integrity of tight junctions. (A) Alveoli, (B) Tight junction, (C) Lung infection by SARS-CoV-2, (D) Tight junction disruption caused by virus interleukin 6, tumor necrosis factor and interferon α, (E) SARS-CoV-2 entrance, (F) Administration of azithromycin, and (G) Restoration of tight junctions.