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. 2020 Sep 23;2:100056. doi: 10.1016/j.ijpx.2020.100056

Fig. 2.

Fig. 2

PPCL-46 spheroidal integrity after treatment with GemHCl and 4NSG at different concentrations. The 4NSG treated PPCL-46 spheroids exhibited irregular or non-spheroidal shapes with increased spheroidal surface area as 4NSG concentration increases. While GemHCl treated spheroids were observed to have a smaller surface spheroidal area with less non-spheroidal shapes. Appearance of non-spheroidal shapes clearly indicates spheroids disruption and a reflection of cell loss due to high anticancer activity due to 4NSG compared with GemHCl.