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In-vivo efficacy of 4NSG in PDX mouse model. Tumor growth curves of GemHCl and 4NSG treated mice bearing pancreatic PDX tumor (A), Terminal tumor weight of treated mice (B), Picture of tumors harvested from control, GemHCl and 4NSG treated mice (C), mouse body weight changes during treatment (D). Asterisks represent level of significance between control and treatment group (*p < 0.05, **p < 0.01). All data represents mean ± SD, (n = 6/group).
