Table 3.
Distribution of Different HR-HPV Genotypes Model According to Histologic Diagnosis in Women with ASC-US. (N=2393)
| HR-HPV Types Model | Histologic Diagnosis | ||
|---|---|---|---|
| Normal/CIN1 N=2151, n (%) | CIN2+ N=242, n (%) | P-value | |
| HR-HPV | 909 (42.3%) | 230 (95.0%) | <0.001 |
| HPV16 | 110 (5.1%) | 116 (47.9%) | <0.001 |
| HPV18 | 71 (3.3%) | 17 (7.0%) | 0.004 |
| HPV31 | 51 (2.4%) | 13 (5.4%) | 0.006 |
| HPV33 | 57 (2.6%) | 14 (5.8%) | 0.006 |
| HPV35 | 23 (1.1%) | 3 (1.2%) | 1.000 |
| HPV39 | 64 (3.0%) | 5 (2.1%) | 0.423 |
| HPV45 | 29 (1.3%) | 4 (1.7%) | 0.925 |
| HPV51 | 98 (4.6%) | 5 (2.1%) | 0.070 |
| HPV52 | 284 (13.2%) | 45 (18.6%) | 0.021 |
| HPV56 | 75 (3.5%) | 6 (2.5%) | 0.411 |
| HPV58 | 150 (7.0%) | 51 (21.1%) | <0.001 |
| HPV59 | 56 (2.6%) | 6 (2.5%) | 0.908 |
| HPV66 | 58 (2.7%) | 2 (0.8%) | 0.078 |
| HPV68 | 65 (3.0%) | 2 (0.8%) | 0.050 |
| HPV16/18a | 178 (8.3%) | 131 (54.1%) | <0.001 |
| HPV16/18/58b | 314 (14.6%) | 174 (71.9%) | <0.001 |
| HPV16/18/52/58c | 568 (26.4%) | 203 (83.9%) | <0.001 |
| HPV16/18/33/52/58d | 611 (28.4%) | 212 (87.6%) | <0.001 |
| HPV16/18/31/33/52/58e | 645 (30.0%) | 221 (91.3%) | <0.001 |
Notes: aWomen with HPV16 and/or HPV18 infection; ball women with any positive of HPV16, HPV18, and HPV58; call women with any positive of HPV16, HPV18, HPV52 and HPV58; dall women with any positive of HPV16, HPV18, HPV33, HPV52 and HPV58; eall women with any positive of HPV16, HPV18, HPV31, HPV33, HPV52 and HPV58.
Abbreviations: HR-HPV, high-risk human papillomavirus, including types HPV-16, −18, −31, −33, −35, −39, −45, −51, −52, −56, −58, −59, −66, −68; CIN, cervical intraepithelial neoplasia; CIN2+, cervical intraepithelial neoplasia grade 2 or worse; ASC-US, atypical squamous cells of undetermined significance.