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Circ_CDR1as depletion inactivates MEK/ERK pathway by regulating miR-1287/Raf1 axis. Hep3B and Huh7 cells are introduced with si-NC, si-circ_CDR1as, si-circ_CDR1as+anti-miR-NC, si-circ_CDR1as+anti-miR-1287, si-circ_CDR1as+pcDNA or si-circ_CDR1as+Raf1. (A and B) Western blot analysis for the protein levels of MEK1, p-MEK1, ERKs and p-ERKs in treated cells. *P < 0.05.
