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. 2020 Sep 15;10:1482. doi: 10.3389/fonc.2020.01482

Figure 3.

Figure 3

SYPL1 was related to cell proliferation and apoptosis. (A) Correlation coefficients (r) between SYPL1 and GSVA scores of KEGG pathways were calculated. Twenty-six pathways with r > 0.1 in GSE15471, GSE16515, GSE28735, TCGA, and PACA-AU or pathways with r < −0.1 in these datasets were identified as pathways related to SYPL1. (B) The GSVA score of the KEGG cell cycle gene set in SYPL1-high and SYPL1-low samples. (C) The GSVA score of the KEGG DNA replication gene set in SYPL1-high and SYPL1-low samples. (D) The GSVA score of the KEGG P53 pathway gene set in SYPL1-high and SYPL1-low samples (Both tumor tissues and adjacent tumor tissues of GSE15471, GSE16515, and GSE28735 were taken into analysis in (B–D), while TCGA and PACA-AU included only tumor tissues). *p < 0.05, **p < 0.01, ***p < 0.001, and ****p < 0.0001.