FIGURE 4.

Core, accessory and pan genomes of marine picocyanobacteria. (A) Distribution of clusters of likely orthologous genes (CLOGs) in picocyanobacterial genomes. A CLOG is considered as core in a taxonomic group if it is present in ≥90% of the strains within this group. Sets of core CLOGS are inferred only for taxonomic groups with more than 3 genomes. Strains are labeled as strain_subclade (or higher taxonomic level when no sub-clade has been defined). (B) Evolution of the pan and core genomes for an increasing number of picocyanobacterial genomes (red, 81 genomes), Synechococcus/Cyanobium (orange, 53 genomes) and Prochlorococcus (green, 28 genomes). The gray zone around each curve represents the first and third quartiles around the median of 1,000 samplings by randomly modifying the order of genome integration.