Fig. 2.

Mitochondrial (mt) proteins involved in BD/SZ/MD and their regional specificity. (A) Venn diagram showing the overlap of mt proteins compiled from five different sources (see Supplemental Table S1). (B) Mt proteins specific or common among BD/SZ/MD. (C, D) Heatmaps (C) and line graphs (D; dotted line represent median mRNA expression) of BD/SZ/MD-associated mt proteins showing regionalization of mRNA expression in human brain regions from RNA-sequencing (RNA-seq) datasets of Human Protein Atlas (integrated with GTex and Fantom) and single cell RNA-seq (scRNA-seq) data from Allen Brain Atlas. Bar graph (D, below) shows the number of BD/SZ/MD-related mt proteins that are above or below median mRNA expression across brain regions from the indicated repositories.