Table 1.
Comparison of healed versus not-healed wounds
| Wound Status at 12th Week |
|||
|---|---|---|---|
| Healed (n = 365,659; 58.9%), n (%) | Not Healed (n = 254,697; 41.1%), n (%) | p | |
| Demographic characteristics | |||
| Age category | <0.0001 | ||
| <55 | 84,840 (23.2) | 61,769 (24.3) | |
| 55–64 | 82,030 (22.4) | 57,910 (22.7) | |
| 65–74 | 89,277 (24.4) | 59,054 (23.2) | |
| >75 | 109,512 (30.0) | 75,964 (29.8) | |
| BMI category | <0.0001 | ||
| <18.5 | 4,180 (1.1) | 4,717 (1.9) | |
| 18.5–24 | 30,725 (8.4) | 26,925 (10.6) | |
| 25–29 | 38,736 (10.6) | 28,764 (11.3) | |
| >30 | 99,017 (27.1) | 54,349 (21.3) | |
| Missing | 193,001 (52.8) | 139,942 (54.9) | |
| Sex (female) | 153,052 (41.9) | 108,145 (42.5) | <0.0001 |
| Palliative | 5,176 (1.4) | 10,754 (4.2) | <0.0001 |
| Smoking status | <0.0001 | ||
| Never smoker | 118,640 (32.5) | 77,640 (30.5) | |
| Former smoker | 93,523 (25.6) | 63,343 (24.9) | |
| Current smoker | 41,226 (11.3) | 33,527 (13.2) | |
| Unknown | 112,270 (30.7) | 80,187 (31.5) | |
| Clinical characteristics | |||
| Alzheimer's disease/dementia | 13,656 (3.7) | 13,920 (5.5) | <0.0001 |
| Coronary artery disease | 61,053 (16.7) | 46,068 (18.1) | <0.0001 |
| Congestive heart failure | 55,559 (15.2) | 40,749 (16.0) | <0.0001 |
| Chronic obstructive pulmonary disease | 43,703 (12.0) | 30,403 (11.9) | 0.8586 |
| Diabetes | 220,893 (60.4) | 154,372 (60.6) | 0.1120 |
| Peripheral vascular diseases | 77,959 (21.3) | 67,471 (26.5) | <0.0001 |
| Quadri/paraplegia | 7,681 (2.1) | 11,872 (4.7) | <0.0001 |
| Hypertension | 189,764 (51.9) | 128,880 (50.6) | <0.0001 |
| Number of concurrent wounds | <0.0001 | ||
| 1 | 169,589 (46.4) | 91,799 (36.0) | |
| 2 | 70,977 (19.4) | 52,024 (20.4) | |
| 3 or more | 125,093 (34.2) | 110,874 (43.5) | |
| Wound characteristics | |||
| Wound area (cm2) (mean/SD) | 6.4 (16.5) | 9.7 (19.0) | <0.0001 |
| Wound depth (mm) (mean/SD) | 2.1 (5.0) | 4.1 (8.1) | <0.0001 |
| Wound location | <0.0001 | ||
| Pelvic | 31,801 (8.7) | 32,759 (12.9) | |
| Upper leg | 13,345 (3.7) | 6,980 (2.7) | |
| Lower leg | 153,995 (42.1) | 70,559 (27.7) | |
| Foot | 81,564 (22.3) | 87,863 (34.5) | |
| Toe | 53,544 (14.6) | 39,462 (15.5) | |
| Amputation site | 3,614 (1.0) | 4,199 (1.7) | |
| Other | 27,799 (7.6) | 12,875 (5.1) | |
| Wound classification | <0.0001 | ||
| Full thickness | 157,903 (43.2) | 132,153 (51.9) | |
| Partial thickness | 121,364 (33.2) | 47,575 (18.7) | |
| Superficial | 30,290 (8.3) | 16,710 (6.6) | |
| Unknown | 56,102 (15.3) | 58,259 (22.9) | |
| Wound etiology | <0.0001 | ||
| Arterial ulcer | 8,844 (2.4) | 14,842 (5.8) | |
| Diabetic ulcer | 127,129 (34.8) | 98,792 (38.8) | |
| Pressure ulcer | 54,500 (14.9) | 57,514 (22.6) | |
| Venous ulcer | 97,047 (26.5) | 44,035 (17.3) | |
| Other | 78,139 (21.4) | 39,514 (15.5) | |
| Necrotic wound tissue | 97,392 (26.6) | 88,797 (34.9) | <0.0001 |
| Infected wound | 124,198 (34.0) | 99,026 (38.9) | <0.0001 |
| Heavily exuding wound | 98,921 (27.1) | 81,616 (32.0) | <0.0001 |
| Eschar formation | 24,500 (6.7) | 28,960 (11.4) | <0.0001 |
BMI, body mass index; SD, standard deviation.