Table 6.
Genetic risk score with the A allele of rs12551256 (IL33) + T allele of rs4925648 (NLRP3) + T allele of rs7925706 (CASP1) both association with risk for asthma.
| Asthma |
||||
|---|---|---|---|---|
| Risk allele | Controls | Cases | Odds Ratioa/95% Confidence interval | P-value |
| 0 | 55 (17.6%) | 6 (8%) | 1.00 | – |
| 1 | 257 (82.4%) | 69 (92%) | 2.47 (1.01–6.04) | 0.029 |
| 2 | 368 (87%) | 113 (95%) | 3.00 (1.24–7.24) | 0.006 |
| 3 | 150 (73.2%) | 50 (89.3%) | 3.15 (1.27–7.86) | 0.006 |
| 4 | 32 (36.8%) | 16 (72.7%) | 5.77 (1.89–17.60) | 9E-04 |
a
Adjusted for confounding variables.