Table 5.
Cytokines level production by ConA stimulated spleen cells of female and male pups of Wistar rat 1 day after LPS injection.
| Cytokine, pg/ml | Groups | Sex | Pf-m | |
|---|---|---|---|---|
| Female | Male | |||
| IL-2 | Control1 (n = 8) | 8000 (6672–8000) | 3214 (1136–3619) | 0.02 |
| LPS2 (n = 10) | 2865 (636–6138) | 459.7 (0–1034) | 0.03 | |
| P1–2 | 0.003 | 0.02 | ||
| IL-4 | Control1 (n = 8) | 47.2 (7.2–126.3) | 15.6 (12.6–51.2) | 0.07 |
| LPS2 (n = 10) | 8.3 (0.5–44.5) | 8.8 (3.5–14.3) | 0.5 | |
| P1–2 | 0.03 | 0.04 | ||
| IL-6 | Control1 (n = 8) | 1992 (1634–2976) | 1925 (529–3322) | 0.8 |
| LPS2 (n = 10) | 2243 (1392–3492) | 3173 (1680–3793) | 0.9 | |
| P1–2 | 0.8 | 0.5 | ||
| TNF-α | Control1 (n = 8) | 266.8 (41.6–820.9) | 246.5 (134.6–372.6) | 0.4 |
| LPS2 (n = 10) | 19.1 (0–85.2) | 53.2 (42.9–68.2) | 0.4 | |
| P1–2 | 0.03 | 0.02 | ||
| IFN-γ | Control1 (n = 8) | 85.5 (13.7–695.2) | 9.8 (5.8–219.8) | 0.2 |
| LPS2 (n = 10) | 61.4 (7.8–211.3) | 9.8 (6.8–21.9) | 0.5 | |
| P1–2 | 0.4 | 0.8 | ||
Bold - statistically significant difference, p < 0.05.