Table 1.
Patient characteristics of women according to their HPV status (hrHPV+ or hrHPV-). P values were calculated using a t-test for the age and a Fisher's exact test for disease status, ethnicity, parity, smoking, contraception and menopause. A P value < 0.05 was considered significant.
| Patient Characteristics | hrHPV+ (N = 65) | hrHPV- (N = 65) | P value |
|---|---|---|---|
| Age | |||
| Mean (SD, range) | 36.6 (9.9, 25–69) | 34.3 (7.9, 23–64) | 0.139 |
| Disease Status, n/N (%) | <0.0001 | ||
| Normal* /HPV | 12/65 (18.5) | 43/65 (66.2) | |
| CIN1 | 13/65 (20.0) | 17/65 (26.1) | |
| CIN2 | 21/65 (32.3) | 2/65 (3.1) | |
| CIN3 | 14/65 (21.5) | 3/65 (4.6) | |
| Cancer | 5/65 (7.7) | 0/65 (0.0) | |
| Ethnicity, n/N (%) | 0.077 | ||
| Caucasian | 56/65 (86.2) | 51/65 (78.5) | |
| Asian | 6/65 (9.2) | 3/65 (4.6) | |
| Black | 3/65 (4.6) | 7/65 (10.8) | |
| Mixed⁎⁎ | 0/65 (0.0) | 4/65 (6.1) | |
| Parity, n/N (%) | 1.000 | ||
| Nulliparous | 46/65 (70.8) | 48/65 (73.9) | |
| Parous | 16/65 (24.6) | 17/65 (26.1) | |
| Unknown | 3/65 (4.6) | 0/65 (0.0) | |
| Smoking Status, n/N (%) | 0.302 | ||
| Current smoker | 18/65 (27.7) | 13/65 (20.0) | |
| Non/Ex-smoker | 44/65 (67.7) | 52/65 (80.0) | |
| Unknown | 3/65 (4.6) | 0/65 (0.0) | |
| Contraception, n/N (%) | 0.653 | ||
| Nil | 24/65 (36.9) | 28/65 (43.1) | |
| Condoms | 12/65 (18.5) | 11/65 (16.9) | |
| COCP/POP | 16/65 (24.6) | 14/65 (21.5) | |
| IUCD/IUD/Mirena/Contraceptive (injection/depot/implant/patch) | 6/65 (9.2) | 11/65 (16.9) | |
| Unknown | 7/65 (10.8) | 1/65 (1.6) | |
| Menopause, n/N (%) | 0.719 | ||
| Pre-menopausal | 60/65 (92.3) | 57/65 (87.7) | |
| Post-menopausal | 5/65 (7.7) | 3/65 (4.6) | |
| Unknown | 0/65 (0.0) | 5/65 (7.7) |
⁎
Normal includes: diagnosis confirmed after histology (n = 32) and cytology (n = 17).
⁎⁎
Mixed includes: Afro-Caribbean/Irish; White African; Afro-Caribbean/British.