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Circadian Parameters Retrieved with Cosinor Analysis for a 48 h Time Course RT-qPCR Data (BMAL1, PER2, and NR1D1).
| Cosinor Analysis | |||
|---|---|---|---|
| Panc1 |
|||
| BMAL1 | PER2 | NR1D1 | |
| Phase (h) | 17.0 ± 0.5 | 4.1 ± 0.7 | 14.4 ± 0.5 |
| Period (h) | 19.0 ± 1.0 | 18.3 ± 1.5 | 18.6 ± 0 |
| Amplitude | 0.2 ± 0.1 | 0.2 ± 0.1 | 0.1 ± 0.1 |
| p Value | <0.0001 | <0.0001 | 0.045 |
| AsPC1 |
|||
|---|---|---|---|
| BMAL1 | PER2 | NR1D1 | |
| Phase (h) | 14.4 ± 0.3 | 0 ± 3.6 | 20 ± 0.0 |
| Period (h) | 22.3. ± 0.9 | 24.8 ± 0.0 | 20.0 ± 1.3 |
| Amplitude | 0.3 ± 0.0 | 0.2 ± 0.1 | 0.2 ± 0.1 |
| p Value | <0.0001 | <0.0001 | 0.0003 |
