| Antibodies |
|
|
| Mouse monoclonal anti-CD9 (clone MM2/57) |
Millipore |
Cat#CBL162; RRID: AB_2075914 |
| Mouse monoclonal anti-CD81 (clone B11) |
Santa Cruz |
Cat#cs166029; RRID: AB_2275892 |
| Mouse monoclonal anti-Tsg101 (clone c-2) |
Santa Cruz |
Cat#sc7965: RRID AB_671392 |
| Rabbit polyclonal anti-beta-actin |
Cell Signaling |
Cat#4967; RRID: AB_330288 |
| Mouse monoclonal anti-syntenin-1 |
Santa Cruz |
Cat#sc100336; RRID: AB_2183156 |
| Mouse monoclonal anti-Mac-2BP |
Santa Cruz |
Cat#sc374541; RRID: AB_10989981 |
| Mouse monoclonal anti-stomatin |
Santa Cruz |
Cat#sc376869 |
| Mouse monoclonal anti-beta-2-microglobulin (clone G-10) |
Santa Cruz |
Cat#sc46697; RRID: AB_626749 |
| Mouse monoclonal anti-moesin (clone E-10) |
Santa Cruz |
Cat#sc13122; RRID: AB_627962 |
| Mouse monoclonal anti-RhoV (clone F-2) |
Santa Cruz |
Cat#sc515072 |
| Mouse monoclonal anti-moesin (clone E-10) AF647 |
Santa Cruz |
Cat#sc13122; RRID: AB_627962 |
| Mouse beta-2-microglobulin (BBM.1) |
Santa Cruz |
Cat#sc13565; RRID: AB_626748 |
| Biological Samples |
|
|
| Human pancreatic cancer and adjacent normal pancreas tissue; matched blood |
Memorial Sloan Kettering Cancer Center |
See Table S1 for a list of patients included |
| Human lung cancer and adjacent or distal normal lung tissue; matched blood |
Memorial Sloan Kettering Cancer Center |
See Table S1 for a list of patients included |
| Human malignant resected tissues |
Memorial Sloan Kettering Cancer Center |
See Table S1 for a list of patients included |
| Healthy donor blood |
Memorial Sloan Kettering Cancer Center |
See Table S1 for a list of donors included |
| Human bodily fluids (bile, lymph) |
Memorial Sloan Kettering Cancer Center |
See Method Details
|
| Human bone marrow |
HemaCare |
N/A |
| Patient-derived xenografts (PDX) |
Dr. V. Rajasekhar |
N/A |
| Critical Commercial Assays |
|
|
| Human DAF ELISA Kit (CD55) |
Abcam |
Cat#ab256405 |
| Human Carbonic Anhydrase 2 (CA2) ELISA Kit |
Abcam |
Cat#ab222881 |
| Human Lactoferrin ELISA Kit |
Abcam |
Cat#ab200015 |
| Deposited Data |
|
|
| Proteomic MS data |
This paper |
https://www.ebi.ac.uk/pride/archive/projects/PXD018301/ |
| Experimental Models: Cell Lines |
|
|
| Human: MDA-MB-231 |
Dr. J. Massague; Minn et al., 2005
|
N/A |
| Human: MDA-MB-1833 |
Dr. J. Massague; Kang et al., 2003
|
N/A |
| Human: MDA-MB-4175 |
Dr. J. Massague; Minn et al., 2005
|
N/A |
| Human: MDA-MB-831 |
Dr. J. Massague; Bos et al., 2009
|
N/A |
| Human: MDA-MB-4173 |
Dr. A. Minn; Minn et al., 2005
|
N/A |
| Human: MDA-MB-4180 |
Dr. A. Minn; Minn et al., 2005
|
N/A |
| Human: MDA-MB-231BR |
Dr. P. Steeg; Yoneda et al., 2001
|
N/A |
| Human: uveal melanoma |
Dr. V. Rajasekhar |
N/A |
| Human: 131/4-5B2 |
Dr. R. Gladdy; Cruz-Munoz et al., 2008
|
N/A |
| Human: 131/8-2L |
Dr. R. Gladdy; Cruz-Munoz et al., 2008
|
N/A |
| Human: CCG9911 |
Dr. A. Kentis |
N/A |
| Human: CLS1 |
Dr. A. Kentis |
N/A |
| Human: MCF10A |
ATCC |
CRL-10317 |
| Human: MDA-MB-468 |
ATCC |
HTB-132 |
| Human: VCAP |
ATCC |
CRL-2876 |
| Human: HT-29 |
ATCC |
HTB-38 |
| Human: MIA PaCa-2 |
ATCC |
CRM-CRL-1420 |
| Human: Kasumi-1 |
ATCC |
CRL-2724 |
| Human: SNU-1 |
ATCC |
CRL-5971 |
| Human: SNU-16 |
ATCC |
CRL-5974 |
| Human: LNCap |
ATCC |
CRL-1740 |
| Human: HCT116 |
ATCC |
CCL-247 |
| Human: SW620 |
ATCC |
CCL-227 |
| Human: Rhabdomyosarcoma |
Dr. R. Gladdy |
CT-10, RD |
| Human: Saos-2 |
ATCC |
HTB-85 |
| Human: U-2 OS |
ATCC |
HTB-96 |
| Human: SK-NP-DW |
Dr. A. Narendran |
N/A |
| Human: PANC-1 |
ATCC |
CRL-1469 |
| Human: AsPC-1 |
ATCC |
CRL-1682 |
| Human: melanoma |
MSKCC |
SK-Mel03 |
| Human: melanoma |
MSKCC |
A375M |
| Human: melanoma |
MSKCC |
A375P |
| Human: PC-3 |
ATCC |
CRL-1435 |
| Human: DU 145 |
ATCC |
HTB-81 |
| Human: BxPC-3 |
ATCC |
CRL-1687 |
| Human: HPAF-II |
ATCC |
CRL-1997 |
| Human: NCI-H1650 |
ATCC |
CRL-5883 |
| Human: NCI-H1975 |
ATCC |
CRL-5908 |
| Human: NCI-H292 |
ATCC |
CRL-1848 |
| Human: NCI-H358 |
ATCC |
CRL-5807 |
| Human: NCI-H2228 |
ATCC |
CRL-5935 |
| Human: A549 |
ATCC |
CRM-CCL-185 |
| Human: 1118A |
Drs. P. Gao, J. Bromberg |
N/A |
| Human: ET2B |
Drs. P. Gao, J. Bromberg |
N/A |
| Human: PC-9 |
Drs. P. Gao, J. Bromberg |
N/A |
| Human: Nalm6 |
ATCC |
CRL-3273 |
| Human: K-562 |
DSMZ |
ACC10 |
| Human: NB-4 |
DSMZ |
ACC207 |
| Human: SK-BR-3 |
ATCC |
HTB-30 |
| Human: mammary epithelial cells |
City of Hope |
N/A |
| Human: mammary epithelial and fibroblasts |
Dr. M. Bissell |
N/A |
| Human: 143B |
ATCC |
CRL-8308 |
| Human: SK-ES-1 |
ATCC |
HTB-86 |
| Human: SK-N-BE(2) |
ATCC |
CRL-2271 |
| Human: IMR5 |
Dr. A. Narendran |
N/A |
| Human: HepG2 |
Dr. R. Schwartz |
N/A |
| Human: S1 |
Dr. M. Bissell; Weaver et al., 2002
|
N/A |
| Human: T4-2 |
Dr. M. Bissell; Weaver et al., 2002
|
N/A |
| Human: MCF-7 |
ATCC |
HTB-22 |
| Human: WI38 |
ATCC |
CCL-75 |
| Human: HIEC-6 |
ATCC |
CRL-3266 |
| Human: NIH/3T3 |
ATCC |
CRL-1658 |
| Human: H2373 |
NCI-H2373 |
N/A |
| Human: H-MESO-1 |
NCI-DCTD |
N/A |
| Human: LP-9 |
Dr. A. Shukla |
CVCL_E109 |
| Human: ORT |
Dr. A. Shukla |
CVCL_N815 |
| Human: HGC27 |
Dr. A. Shukla |
CVCL_1279 |
| Human: NAMALWA |
ATCC |
CRL-1432 |
| Human: MKN45 |
ACCEGEN |
ABC-TC0687 |
| Human: C4-2B |
ATCC |
CRL-3315 |
| Human: WERI-Rb-1 |
ATCC |
HTB-169 |
| Human: Y79 |
ATCC |
HTB-18 |
| Human: DLD-1 |
ATCC |
CCL-221 |
| Human: HEK293 |
ATCC |
CRL-1573 |
| Mouse: B16-F0 |
ATCC |
CRL-6322 |
| Mouse: B16-F1 |
ATCC |
CRL-6323 |
| Mouse: B16-F10 |
ATCC |
CRL-6475 |
| Mouse: 4T1 |
ATCC |
CRL-2539 |
| Mouse: 67NR |
Dr. J. Bromberg |
N/A |
| Mouse: 168FARN |
Barbara Ann Karmanos Cancer Center |
N/A |
| Mouse: Pan02 |
NCI Tumor Repository |
N/A |
| Mouse: E0771 |
Dr. J. Bromberg |
N/A |
| Mouse: LLC1 (LL/2) |
ATCC |
CRL-1642 |
| Mouse: CT26 |
ATCC |
CRL-2683 |
| Mouse: K7M2 |
ATCC |
CRL-2836 |
| Mouse: Melan-A |
Ximbio |
CVCL_4624 |
| Experimental Models: Organisms/Strains |
|
|
| Mouse: wild type C57BL/6 |
Jackson Laboratory |
Cat#000664 |
| Mouse: PyMT (Tg(MMTV-PyVT)634Mul) |
Jackson Laboratory |
Cat#002374 |
| Mouse: Pdx1Cre;Lsl-KrasG12D;Lsl-TP53R172H (KPC) |
Dr. B. Stanger; Hingorani et al., 2005
|
N/A |
| Mouse: NOD/SCID/γc−/− (NSG) |
Jackson Laboratory |
Cat#005557 |
| Mouse: wild type BALB/c |
Jackson Laboratory |
Cat#000651 |
| Mouse: athymic nude (Foxn1nu) |
Jackson Laboratory |
Cat#002019 |
| Software and Algorithms |
|
|
| Proteome Discoverer 1.4.1.14 |
Thermo Scientific |
https://www.thermofisher.com/us/en/home.html |
| Mascot 2.5 |
Matrix Science |
http://www.matrixscience.com/ |
| R, v3.2.5 |
The R Foundation |
https://www.r-project.org |
| GSEA, MSigDB v5.1 |
UC San Diego and Broad Institute |
https://www.broadinstitute.org/gsea/msigdb/index.jsp |
