Table 2. Summary of Gluten Introduction in Prevention RCTs.

Study	No.	Population	Age at introduction of gluten in intervention vs control groups, mo	Weekly quantity of gluten recommended during intervention period, g	Weekly volume of gluten consumed during intervention period
PreventCD3	944	High risk (HLA-DQ or HLA-DQ8 positive)	4-6 vs >6	0.7	No set quantity recorded; 416/475 received at least 0.53 g/wk
BABYDIET4	150	First-degree relative with type 1 diabetes and a risk HLA genotype	6 vs 12	No set quantity stipulated	No set quantity recorded
CELIPREV5	707	First-degree relative with CD	6 vs 12	No set quantity stipulated	No set quantity recorded; mean, 3.2 g/d at age 9 mo
EAT12	1004	General population	4-6 vs >6	3.2	2.89

Abbreviations: CD, celiac disease; CELIPREV, the Risk of Celiac Disease and Age at Gluten Introduction study; EAT, Enquiring About Tolerance; HLA, human leukocyte antigen; RCTs, randomized clinical trials.