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. 2019 Dec 17;11(1):111–117. doi: 10.1039/c9md00341j

Table 3. Antibacterial solubility profiles in DMSO and Cyrene™.

Antibacterial Cyrene™ stock preparation DMSO stock preparation
Tetracycline 10 mM in Cyrene™ 10 mM in DMSO
Vancomycin hydrochloride 10 mM in 50/50 Cyrene/water 10 mM in 50/50 DMSO/water
Ciprofloxacin hydrochloride 10 mM in 50/50 Cyrene/water 10 mM in 50/50 DMSO/water
Colistin sulfate 10 mM in 50/50 Cyrene™/water (adjusted to 5 mM in 25/75 Cyrene/water for later comparison purposes) 5 mM in 25/75 DMSO/water
Penicillin G sodium 6.7 mM in 33/66 Cyrene™/water 10 mM in 50/50 DMSO/water (adjusted to 6.7 mM in 33/66 Cyrene/water for later comparison purposes)
Polymixin B sulfate 10 mM in 50/50 Cyrene™/water Not soluble in DMSO/water down to 10% DMSO (10 mM in water used for later comparison purposes)
Tobramycin 10 mM in 50/50 Cyrene™/water 10 mM in 50/50 DMSO/water
Levofloxacin 10 mM in Cyrene™ 10 mM in DMSO