Table 1.
Variations in anatomic distribution of cutaneous squamous cell carcinoma by patient age and sex and tumor invasiveness.
| Overall |
Invasiveness |
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| In situ |
Invasive |
|||||||||||||||
| Location | Total | Female | Male | p-value | Total | Female | Male | p-value | Total | Female | Male | p-value | ||||
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | ||||||||
| Head and necka | 849 (40.2) | 164 (20.9) | 685 (51.7) | <0.001 | 337 (41.2) | 91 (29.5) | 246 (48.3) | <0.001 | 512 (39.6) | 73 (15.3) | 439 (53.8) | <0.001 | ||||
| Upper extremitiesb | 537 (25.4) | 192 (24.4) | 345 (26.0) | 0.412 | 210 (25.7) | 70 (22.6) | 140 (27.5) | 0.124 | 327 (25.3) | 122 (25.6) | 205 (25.1) | 0.856 | ||||
| Trunkc | 253 (12.0) | 86 (10.9) | 167 (12.6) | 0.256 | 115 (14.1) | 28 (9.1) | 87 (17.1) | 0.001 | 138 (10.7) | 58 (12.2) | 80 (9.8) | 0.186 | ||||
| Buttocks | 21 (1.0) | 20 (2.6) | 1 (0.1) | <0.001 | 6 (0.7) | 6 (1.9) | 0 (0) | 0.002 | 15 (1.2) | 14 (2.9) | 1 (0.1) | <0.001 | ||||
| Lower extremitiesd | 451 (21.4) | 324 (41.2) | 127 (9.6) | <0.001 | 150 (18.3) | 114 (36.9) | 36 (7.1) | <0.001 | 301 (23.3) | 210 (44.0) | 91 (11.2) | <0.001 | ||||
| Age < 65 years | Age ≥ 65 years | |||||||||||||||
| In situ |
Invasive |
In situ |
Invasive |
|||||||||||||
| Location | Total | Female | Male | p-value | Total | Female | Male | p-value | Total | Female | Male | p-value | Total | Female | Male | p-value |
| n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | n (%) | |||||
| Head and necka | 105 (41.5) | 23 (27.1) | 82 (48.8) | 0.001 | 147 (39.1) | 22 (14.1) | 125 (56.8) | <0.001 | 232 (41.1) | 68 (30.4) | 164 (48.1) | <0.001 | 365 (39.8) | 51 (15.9) | 314 (52.7) | <0.001 |
| Upper extremitiesb | 70 (27.7) | 18 (21.2) | 52 (30.9) | 0.101 | 93 (24.7) | 41 (26.3) | 52 (23.7) | 0.558 | 140 (24.8) | 52 (23.2) | 88 (25.8) | 0.485 | 234 (25.5) | 81 (25.2) | 153 (25.7) | 0.885 |
| Trunkc | 34 (13.4) | 7 (8.2) | 27 (16.1) | 0.084 | 52 (13.8) | 24 (15.4) | 28 (12.7) | 0.462 | 81 (14.3) | 7 (8.2) | 60 (17.6) | 0.006 | 86 (9.4) | 34 (10.6) | 52 (8.7) | 0.355 |
| Buttocks | 6 (2.4) | 6 (7.0) | 0 (0) | <0.001 | 12 (3.2) | 12 (7.7) | 0 (0) | <0.001 | 0 (0) | 0 (0) | 0 (0) | – | 3 (0.3) | 2 (0.6) | 1 (0.2) | 0.249 |
| Lower extremitiesd | 38 (15.0) | 31 (36.5) | 7 (4.2) | <0.001 | 72 (19.2) | 57 (36.5) | 15 (6.8) | <0.001 | 112 (19.8) | 83 (37.0) | 29 (8.5) | <0.001 | 229 (25.0) | 153 (47.7) | 76 (12.7) | <0.001 |
a
Head and neck includes the face, eyelids, scalp, ears, and neck.
b
Upper extremities includes the arms, hands, and shoulders.
c
Trunk includes the back, chest, and abdomen.
d
Lower extremities includes the thighs, legs, and feet.