Table 4.

Univariate and multivariate Cox regression analysis of m⁶A regulators for overall survival in patients with STAD.

Variable	Univariate			Multivariate
	HRa	95% CI	p-valueb	HRa	95% CI	p-valueb
Age (>65 vs ≤65)	0.998	0.993–1.004	0.606
Gender	1.454	0.952–2.219	0.083
Grade	1.342	0.923–1.951	0.124
Stage	1.516	1.200–1.915	<0.001	1.33	0.927–1.908	0.122
T	1.311	1.028–1.672	0.029	1.075	0.778–1.485	0.661
M	1.751	0.882–3.475	0.109
N	1.268	1.065–1.510	0.008	1.134	0.899–1.430	0.288
Risk score	2.949	1.720–5.055	<0.001	3.283	1.866–5.778	<0.001

m⁶A, N⁶-methyladenosine; STAD, stomach adenocarcinoma; HR, hazard ratio; CI, confidence interval; T, N, M, tumor, node, metastasis.

^aValues >1.0 indicate that expression is positively associated with poor survival.

^bLikelihood ratio test p-value; significant values <0.05.