Table 2.
Between-group differences in the causal influences from and to the bilateral DLPFC.
Cluster Location | MNI Coordinates (x, y, z) | Mean (SE) GCA Coefficient in HC Group | Mean (SE) GCA Coefficient in OCD Group | Cluster Size | t Value | p-FWE |
---|---|---|---|---|---|---|
Causal Influence of Left DLPFC on Whole Brain | ||||||
Right Supplementary Motor Area | 3, 3, 54 | 0.005(0.008) | −0.049(0.009) | 131 | −3.91 | 0.035 |
Causal influence of Whole Brain on Left DLPFC | ||||||
Right Dorsal Anterior Cingulate Cortex | 7, −12, 49 | 0.009(0.012) | 0.091(0.012) | 125 | 5.08 | 0.025 |
Left Fusiform Gyrus | −63, −42, −18 | 0.008(0.009) | −0.051(0.008) | 143 | −4.72 | 0.015 |
Causal Influence of Right DLPFC on Whole Brain | ||||||
Left Inferior Temporal Gyrus | −57, −15, −27 | −0.001(0.004) | 0.031(0.004) | 246 | 4.67 | 0.007 |
Causal Influence of Whole Brain on Right DLPFC | ||||||
Cerebellum | −18, −57, −21 | −0.013(0.010) | 0.065(0.010) | 411 | 4.58 | <0.001 |
Right Orbitofrontal Cortex | 33, 39, −15 | 0.019(0.008) | −0.037(0.007) | 99 | −4.66 | 0.038 |
Left Inferior Temporal Gyrus | −42, 6, −45 | 0.013(0.007) | −0.057(0.008) | 304 | −4.79 | <0.001 |
Right Inferior Temporal Gyrus | 45, 12, −45 | 0.002(0.008) | −0.059(0.008) | 164 | −4.36 | 0.005 |
*Positive t values represent OCD > HC; negative t values represent OCD < HC.