Table-4.
Effects of the methanol leaf extract of Momordica charantia on Antioxidant enzymes of hepatic tissues of alloxan-elicited diabetic rats.
| Parameter | Group A | Group B | Group C | Group D | Group E |
|---|---|---|---|---|---|
| GPx | 32.31±1.86 | 21.57±1.85α | 32.48±1.17β | 33.51±1.95β | 33.87±1.41β |
| GST | 0.31±0.09 | 0.22±0.05α | 0.30±0.02β | 0.28±0.09β | 0.30±0.05β |
| SOD | 11.33±1.43 | 9.57±1.20α | 94.04±2.59β | 12.22±0.77β | 11.78±0.54β |
Results expressed in Mean±SD, n=10. αSignificant reduction when compared with normal control, βSignificant increase when compared with diabetic control at α0.05. GPx=Glutathione peroxidase, (µmol/mg protein), GST=Glutathione S-transferase (mmol 1-chloro-2,4-dinitrobenzene-GSH complex formed/min/mg protein), SOD=Superoxide dismutase, units/mg protein. Group A NDNT=Non-diabetic non-treated, Group B DNT=Diabetic non-treated, Group C (diabetic treated with glibenclamide), Group D (diabetic treated with 200 mg/kg MC), Group E (diabetic treated 400 mg/kg MC)