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. 2020 Aug 8;13(8):1528–1535. doi: 10.14202/vetworld.2020.1528-1535

Table-4.

Effects of the methanol leaf extract of Momordica charantia on Antioxidant enzymes of hepatic tissues of alloxan-elicited diabetic rats.

Parameter Group A Group B Group C Group D Group E
GPx 32.31±1.86 21.57±1.85α 32.48±1.17β 33.51±1.95β 33.87±1.41β
GST 0.31±0.09 0.22±0.05α 0.30±0.02β 0.28±0.09β 0.30±0.05β
SOD 11.33±1.43 9.57±1.20α 94.04±2.59β 12.22±0.77β 11.78±0.54β

Results expressed in Mean±SD, n=10. αSignificant reduction when compared with normal control, βSignificant increase when compared with diabetic control at α0.05. GPx=Glutathione peroxidase, (µmol/mg protein), GST=Glutathione S-transferase (mmol 1-chloro-2,4-dinitrobenzene-GSH complex formed/min/mg protein), SOD=Superoxide dismutase, units/mg protein. Group A NDNT=Non-diabetic non-treated, Group B DNT=Diabetic non-treated, Group C (diabetic treated with glibenclamide), Group D (diabetic treated with 200 mg/kg MC), Group E (diabetic treated 400 mg/kg MC)