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. 2020 Sep 28;10:15873. doi: 10.1038/s41598-020-71948-1

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Manhattan plots showing the association of FADS locus variation with levels of four n-6 LC-PUFA-containing molecules: ARA, 2-ARA glycerol, 1-stearoyl-2-ARA-GPC and 1-ARA-2-lyso-GPC. The horizontal axis shows the physical location in the genome, organized by chromosome. The vertical axis shows the − log₁₀-transformed p values from the association analysis with the red line indicating the genome-wide significance level (p = 5 × 10^–8). The four peaks show the strong association with the FADS locus.