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. 2020 Sep 29;6:67. doi: 10.1038/s41421-020-00198-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a Interactions between Tom22 and Tom40s. The polar interactions are indicated by red dotted lines. Side views are shown. b The Q-rich segment (sticks) of Tom22 in IMS. Interactions of Tom40 with Tom5 (c), Tom6 (d), Tom7 (e). The polar interactions are indicated by red dotted lines. f, g Knockdown of Tom subunits. The tetramer and intermediate state of TOM complex are indicated by boxes, and are separated for a longer exposure as shown in the bottom of each panel. Tom40 was detected with the antibodies against Tom40.