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. 2020 Sep 29;6:67. doi: 10.1038/s41421-020-00198-2

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a A 8.5-Å-resolution cryo-EM reconstruction of the tetrameric TOM complex. Two dimeric units are indicated by a and b. Cytosol views are shown. b Dimeric TOM complex models fitted in the map. Two dimeric units are indicated by a and b. Side views are shown. c Fitted model of tetrameric TOM complex. Cytosol views are shown. d Interactions between Tom6^F34–R42 and Tom40. The polar interactions are indicated by red dotted lines. Side views are shown. e A potential binding pocket formed by Tom22, Tom7 from one dimer and Tom5 from the other dimer. The potential pocket is indicated with dotted cycles. Side views are shown.