Table 3.
Clinical characteristics and co-receptor tropism in HIV-1B cohort.
| Variables | Overall | Remains CCR5-tropic (NSI-virus) | switches to CXCR4-tropic (SI-virus) | p-value |
|---|---|---|---|---|
| n | 82 | 52 | 30 | N/A |
| Gender (male) | 100% (82) | 100% (52) | 100% (30) | N/A |
| Age (years) at seroconversion | 36.6 [31.3–40.7] | 36.6 [32.8–42.4] | 36.8 [30.2–39.0] | 0.338 |
| CD4+ T-cell count (cells/µL) at 1 year after seroconversion | 605 [450–813] | 610 [490–823] | 570 [408–773] | 0.482 |
| HIV-RNA load (10log copies/mL) at 1 year after seroconversion | 4.5 [3.9–4.8] | 4.4 [3.9–4.8] | 4.5 [4.2–5.0] | 0.192 |
| AIDS diagnosisa | 53.7% (44) | 40.4% (21) | 76.7% (23) | 0.003 |
| Deatha | 41.5% (34) | 28.8% (15) | 63.3% (19) | 0.003 |
Data displayed as percentage (absolute number) or as median [interquartile range].
n number, SI syncytium-inducing, NSI non-SI.
Units and non-significant p-values are displayed in italics. p-values below 0.05 are displayed in bold.
aOccuring during follow-up of median 2520 days [IQR: 1883–3614] after seroconversion.