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. 2020 Sep 15;10:568417. doi: 10.3389/fonc.2020.568417

Table 3.

Adjusted odds ratios of adjuvant chemotherapy administration based on multivariate logistic regression.

Odds ratio 95% CI p
Age
   ≥75 years Ref = 1
    18–64 years 11.69 10.84–12.6 <0.0001
    65–74 years 4.89 4.52–5.29 <0.0001
Gender
    Male Ref = 1
    Female 1.06 1.0–1.12 0.0368
Race
    Black Ref = 1
    White 1.11 1.02–1.21 0.0139
    Hispanic 1.3 1.12–1.49 0.0003
    Others 1.13 0.96–1.34 0.1337
Charlson/deyo score
    2 Ref = 1
    0 2.11 1.88–2.38 <0.0001
    1 1.68 1.48–1.91 <0.0001
Institution
    Non-academic Ref = 1
    Academic 1.19 1.12–1.27 <0.0001
Location
    Pacific Ref = 1
    East North Central 1.4 1.26–1.55 <0.0001
    East South Central 1.26 1.11–1.44 0.0005
    Middle Atlantic 1.62 1.45–1.8 <0.0001
    Mountain 1.05 0.9–1.23 0.5254
    New England 1.16 1.01–1.34 0.0316
    South Atlantic 1.15 1.04–1.27 0.006
    West North Central 1.38 1.22–1.57 <0.0001
    West South Central 1.2 1.06–1.36 0.0043
Insurance
    Uninsured Ref = 1
    Insured 1.1 0.96–1.26 0.1694
Income
    < $30,000 Ref=1
    $30,000–$34,999 1.06 0.97–1.17 0.2071
    $35,000–$45,999 0.98 0.9–1.08 0.7154
   ≥$46,000 1.01 0.93–1.11 0.7599
Year of diagnosis
    2009 Ref = 1
    2004 1.22 1.11–1.34 <0.0001
    2005 1.24 1.13–1.36 <0.0001
    2006 1.37 1.25–1.5 <0.0001
    2007 1.29 1.18–1.41 <0.0001
    2008 1.1 0.99–1.2 0.0526
Primary site
    Right Ref = 1
    Left 1.27 1.19–1.35 <0.0001
    Transverse 1.11 1.02–1.22 0.0194
Grade
    Well–differentiated Ref = 1
    Moderately differentiated 1.14 1.04–1.25 0.0061
    Poor/Undifferentiated 1.76 1.58–1.97 <0.0001
Nodes evaluated
    Adequate (≥ 12) Ref = 1
    Inadequate (<12) 1.15 1.08–1.22 <0.0001
AJCC, pT
    3 Ref = 1
    4 3.54 3.27–3.34 <0.0001
Colectomy
    Total Ref = 1
    Partial 1.08 0.93–1.26 0.3234
    Subtotal 1.14 0.98–1.33 0.0797
Margins
    Negative Ref = 1
    Positive 1.63 1.42–1.87 <0.0001

Ref, Reference.