Table 4.
5-years overall survival analysis using Cox proportional hazards regression model.
| 5-years survival, % | Hazards ratio | 95% CI | p | |
|---|---|---|---|---|
| Age | ||||
| ≥75 years | 45.3 | Ref = 1 | ||
| 18–64 years | 71.9 | 0.45 | 0.43–0.47 | <0.0001 |
| 65–74 years | 65.4 | 0.56 | 0.54–0.58 | <0.0001 |
| Gender | ||||
| Male | 57.6 | Ref = 1 | ||
| Female | 59 | 0.86 | 0.83–0.88 | <0.0001 |
| Race | ||||
| Black | 58.4 | Ref = 1 | ||
| White | 58.2 | 0.9 | 0.86–0.95 | 0.0001 |
| Hispanic | 58.1 | 1.03 | 0.94–1.12 | 0.5622 |
| Others | 63.4 | 0.95 | 0.86–1.06 | 0.3364 |
| Charlson/deyo score | ||||
| 2 | 39.2 | Ref = 1 | ||
| 0 | 62.6 | 0.58 | 0.55–0.61 | <0.0001 |
| 1 | 53.7 | 0.7 | 0.68–0.74 | <0.0001 |
| Institution | ||||
| Non–academic | 58.1 | Ref = 1 | ||
| Academic | 59 | 0.99 | 0.95–1.03 | 0.5834 |
| Location | ||||
| Pacific | 63.8 | Ref = 1 | ||
| East North Central | 58.9 | 1.16 | 1.1–1.24 | <0.0001 |
| East South Central | 57.9 | 1.2 | 1.11–1.3 | <0.0001 |
| Middle Atlantic | 54.5 | 1.32 | 1.24–1.4 | <0.0001 |
| Mountain | 56.7 | 1.27 | 1.16–1.4 | <0.0001 |
| New England | 56.4 | 1.15 | 1.07–1.24 | 0.0002 |
| South Atlantic | 58.7 | 1.16 | 1.1–1.23 | <0.0001 |
| West North Central | 60.1 | 1.12 | 1.04–1.2 | 0.0037 |
| West South Central | 55.6 | 1.31 | 1.22–1.41 | <0.0001 |
| Insurance | ||||
| Uninsured | 58.8 | Ref = 1 | ||
| Insured | 58.3 | 0.71 | 0.64–0.78 | <0.0001 |
| Income | ||||
| < $30,000 | 54.7 | Ref=1 | ||
| $30,000–$34,999 | 56.6 | 0.95 | 0.9–0.99 | 0.0470 |
| $35,000–$45,999 | 59.4 | 0.87 | 0.82–0.91 | <0.0001 |
| ≥$46,000 | 61 | 0.85 | 0.81–0.89 | <0.0001 |
| Year of diagnosis | ||||
| 2009 | 52.4 | Ref = 1 | ||
| 2004 | 59 | 0.79 | 0.75–0.83 | <0.0001 |
| 2005 | 60.7 | 0.75 | 0.71–0.79 | <0.0001 |
| 2006 | 59.7 | 0.78 | 0.74–0.82 | <0.0001 |
| 2007 | 60.2 | 0.79 | 0.75–0.83 | <0.0001 |
| 2008 | 57.9 | 0.86 | 0.81–0.9 | <0.0001 |
| Primary site | ||||
| Left | 59 | Ref = 1 | ||
| Right | 58 | 0.93 | 0.9–0.97 | 0.0003 |
| Transverse | 58 | 0.95 | 0.9–1.00 | 0.0574 |
| Grade | ||||
| Poor/Undifferentiated | 55.2 | Ref = 1 | ||
| Well-differentiated | 60.1 | 0.88 | 0.82–0.93 | <0.0001 |
| Moderately diff | 58.8 | 0.91 | 0.87–0.95 | <0.0001 |
| Nodes evaluated | ||||
| <12, inadequate | 51.4 | Ref = 1 | ||
| ≥12, adequate | 60.6 | 0.74 | 0.71–0.76 | <0.0001 |
| AJCC pT | ||||
| 4 | 46.4 | Ref=1 | ||
| 3 | 59.6 | 0.59 | 0.57–0.62 | <0.0001 |
| Chemotherapy | ||||
| None | 54.3 | Ref = 1 | ||
| Single–agent | 73.9 | 0.55 | 0.51–0.59 | <0.0001 |
| Multi–agent | 73.6 | 0.6 | 0.56–0.64 | <0.0001 |
| Type not known | 72.2 | 0.65 | 0.57–0.73 | <0.0001 |
| Colectomy | ||||
| Total | 54 | Ref = 1 | ||
| Partial | 58.8 | 0.84 | 0.76–0.91 | <0.0001 |
| Subtotal | 58.3 | 0.86 | 0.78–0.94 | 0.0005 |
| Margins | ||||
| Positive | 41.3 | Ref = 1 | ||
| Negative | 58.9 | 0.64 | 0.59–0.68 | <0.0001 |
Ref, Reference.