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[Preprint]. 2020 Sep 16:2020.09.15.299164. [Version 1] doi: 10.1101/2020.09.15.299164

Table 2.

Cellular antiviral assay results of ebselen, disulfiram, carmofur, PX-12, tideglusib, and shikonin against EV-A71 and EV-D68.

EV-A71 CPE assay EC50 (μM)/CC50 (μM)a EV-D68 CPE assay EC50 (μM)/CC50 (μM)
GC-376 0.2 ± 0.1/>50 0.9 ± 0.0/>50
Telaprevir N.T. 0.4 ± 0.1/48.8 ± 4.1
Ebselen >20/17.0 ± 0.70 >10/5.4 ± 0.2
Disulfiram >10/8.3 ± 0.6 >3/1.5 ± 0.1
Tideglusib >20/16.6 ± 1.2 >20/12.8 ± 0.7
Carmofur >50/47.2 ± 4.8 >20/18.5 ± 1.5
Shikonin >1/0.8 ± 0.0 >1/0.4 ± 0.0
PX-12 >10/7.1 ± 0.5 >20/16.5 ± 2.4
a

EC50 and CC50 (μM) = mean ± standard deviation. The values are the mean ± standard deviation from three replicates.