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Serum metabolites in blood samples collected on days 650, 669 and 809 (further details in Fig. 1); 1.3-fold up-regulated (Up) and 0.7-fold down-regulated (Down) molecules were extracted. (A) Overall map of the number of regulated metabolite molecules at different time points. (B) The molecules were classified into seven components. (C) The detailed molecules in the classes ‘Sphingomyelin’, ‘Acyl-alkyl phosphatidylcholine’, and ‘LysoPC’ were specified.
