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PICP and PIIINP levels in RCF cell culture medium from each treatment group.
| Group | Control | HG | HG + Irbesartan | HG + Irbesartan + Pirfenidone |
|---|---|---|---|---|
| PICP (pg/ml) | 615.8±31.9 | 1186.6±43.8a | 926.5±36.9a | 811.8±35.1a |
| PIIINP (pg/ml) | 236.5±18.7 | 458.4±37.5a | 364.3±26.5a | 306.7±24.7a |
aP<0.05 vs. control group. HG, high glucose; PICP, procollagen carboxyl-terminal peptide; PIIINP, procollagen type III N-terminal peptide.
