Table II.

Treatment parameters of 21 patients treated with regorafenib.

Treatment parameters	No. (%)a
Median age at regorafenib initiation, years (range)	70 (35-86)
Median number of therapeutic lines before regorafenib (range)	4 (3-8)
Median duration of regorafenib treatment, months (range)	5.15 (2-20)
Regorafenib dose reduction (due to any reason)	15 (71.4)
Reason for discontinuation of regorafenib
Disease progression	15 (71.4)
Toxicity other than HT	1 (4.8)
Death	1 (4.8)
Not evaluable	4 (19.0)
Median number of systemic treatments after regorafenib failure (range)	1 (0-5)

^aUnless otherwise indicated. HT, hepatic toxicity.