Table 2.

Effect of different antibiotic treatments on attached B. burgdorferi biofilm glycosaminoglycan (GAG) content at 50 µM concentration evaluated with Dimethylmethylene Blue Assay for Glycosaminoglycan after 72 h

Antibiotics	10 µM GAG % ± %SD	50 µM GAG % ± %SD
Control (PBS)	100%	100%
DDS	79% ± 5.8	68% ± 3.6
DOXY	76% ± 4.2	73% ± 7.2
RIF	75% ± 6.3	70% ± 5.8
CEF	78% ± 5.2	76% ± 7.4
AZ	82% ± 6.6	79% ± 8.2
DDS + DOXY	70% ± 8.2	69% ± 5.3
DDS + DOXY + RIF	69% ± 4.2	70% ± 7.3
DDS + DOXY + RIF + AZ	75% ± 6.8	62% ± 5.4

The table summarizes that mean % of the residual GAG amounts with ± SD compared to the PBS treated control. N = 20

DDS dapsone, DOXY doxycycline, RIF rifampin, CEF cefuroxime, AZ azithromycin