Table 2.
Global differences in MNS activation during action observation
| Brain regions with peak activation | Cluster breakdown | |||||
|---|---|---|---|---|---|---|
| Anatomical region | L/R | Total number of voxels | MNI coordinates | SDM-Z | p (uncorrected) | Anatomical regions (Broadmann area) |
| ASD > TD | ||||||
| Inferior frontal gyrus, orbital part | R | 1077 | 48,28, − 4 | 2.827 | ~0 |
Inferior frontal gyrus, orbital part (BA47) Inferior frontal gyrus, orbital part (BA45) Inferior frontal gyrus, triangular part (BA45) |
| Supplementary motor area | L | 525 | − 4,8,54 | 2.044 | < 0.0005 | Supplementary motor area (BA6) |
| Inferior parietal lobule | L | 46 | − 52, − 40,40 | 1.710 | < 0.005 | Inferior parietal lobule (BA40) |
| ASD < TD | ||||||
| Precentral gyrus | L | 692 | − 42, − 6,48 | − 2.169 | < 0.0001 |
Precentral gyrus (BA6) Postcentral gyrus (BA6) |
| Amygdala | R | 68 | 28, − 8, − 24 | − 1.451 | < 0.005 |
Amygdala (BA34) Hippocampus (BA20) Median cingulate |
| Cerebellum, hemispheric lobule VI | R | 17 | 38, − 74, − 20 | − 1.392 | < 0.005 |
Cerebellum, hemispheric lobule VI (BA19) Cerebellum, crus I (BA19) |